GeneWize DNA Assessments FAQ’s
Posted on 08. Mar, 2010 by Vincent Muir in GeneWize Life Sciences, The GeneWize FAQs
When will I receive my DNA Assessment Kit?
DNA Assessment Kits are normally mailed within one week of enrollment.
Are the DNA assessments curative or preventative?
Neither. Their Healthy Aging DNA Assessment™ and Skin Aging Assessment™ is simply an evaluation.
Will I ever have to be re-tested?
There is no need to retake the LifeMap Healthy Aging DNA Assessment™ as your genes never change. In terms of investigating DNA, your DNA is the same all the way through your entire life.
What is the advantage of the LifeMap Healthy Aging (DNA) Assessment™?
The LifeMap Healthy Aging Assessment™ helps provide a scientific basis for more accurately forecasting the unique nutritional supplement needs of each individual. The assessment results create a matrix to direct your custom tailored nutritional supplement regimen and to help you accomplish optimal health and well being. You may say it’s the difference between shooting an arrow at a target in the dark versus shooting an arrow at a target at high noon.
What are SNPs and why is this information significant?
SNPs (pronounced “snips”) are single nucleotide polymorphisms, which are small but common natural differences in human DNA. Each person’s genetic material holds a exclusive SNP pattern attached to the DNA strand that serves as the body’s instruction book, telling the body in minute detail how to do everything from making bone cells to dealing out dietary cholesterol to detoxifying spent hormones in the liver.
Just as no two people are the same, so every instruction book is different. Each person has several million SNPs that account for the wide differences seen in the spectrum of human exterior and physiology. Some of these processes that have a bearing on SNPs and gene expression are more efficient and supportive of health than others. By determining a SNP profile, it is possible to find out which areas are strong and which areas need extra assistance.
How does the LifeMap Healthy Aging Assessment™ DNA collection procedure work?
The DNA Collection procedure begins with a comfortable, easy to perform cheek swab to collect a DNA specimen. Gently swab the inside of your cheek, and then permit the swab to dry in the drying rack that is incorporated with your collection kit. The dried swab is then placed in a special envelope and sent to our lab for investigation. You will receive the results of the evaluation in about two to three weeks with your LifeMap product and/or your report will be made accessible in your online Back Office which is a password protected personal website allocated to you when you register as an Affiliate.
Why shouldn’t I just take handfuls of dietary supplements to cover everything?
Although you can pay for and use a wide variety of nutritional supplements, most health care practitioners would be in agreement that this is neither economical, nor practical. By comprehending your predispositions, from a DNA SNP perspective, we are able to create an individualized nutritional supplement series specifically for you. This targeted approach (rather than a one size fits all supplement approach) ultimately helps save you time, money and more prominently focuses your regimen on key areas that are important to your personal physiology.
What does the process involve?
Everything needed to obtain a DNA sample is included in the DNA collection kit. It’s so easy that you can carry out the collection in less than five minutes. Swab the inside of your mouth (the inner cheek) a number of times with the sterile swabs included in the kit. It’s fast, effortless and simple.
The swabs are then air dried for five minutes in the provided stand, using attention never to touch or taint the tip of the swab (full and easy to follow instructions are incorporated with every collection kit). The sample is then mailed in the already addressed, postage paid envelope.
What is the SNP analysis process and is it confidential?
All SNP collection kits, swab and mailing envelopes are bar coded for tracking and confidentiality.
After receiving the swabs, the lab verifies and uploads the bar coded sample for confidentiality, tracking and control.
The DNA is removed from the swab and the lab amplifies the area of the DNA containing the SNP. The method used to amplify the individual’s DNA is called a polymerase chain reaction (PCR).
The SNP is then detected by using a proprietary technology and an assortment of important quality control systems are in place to make sure accurateness and repeatability.
The consequences of the detected SNPs are then analyzed and compiled by specially programmed computers and interpreted electronically into a confidential report called a LifeMap Healthy Aging Assessment™.
How do you decide which SNPs are assessed in GeneWize LifeMap Healthy Aging ™ DNA assessment?
Although human DNA includes millions of SNPs, GeneLink scientists used the following criteria to choose the SNPs for the GeneWize LifeMap Healthy Aging ™ DNA Assessment:
- Valid – The existence of the SNP is maintained by solid, credible scientific evidence. Gene SNPs are added as knowledge develops.
- Important – A SNP predicts biochemical processes that connect with significant, precise physiologic disadvantages.
- Frequent – The SNP frequency is fairly common among the general population.
- Actionable – A SNP’s negative capability can be ameliorated by nutritional formulations.
What is the discipline that ties nutritional supplementation and lifestyle changes to the predisposition marked by the SNPs?
Leading clinical evidence is more and more linking SNPs to precise nutritional needs. For example: The SNP for methylenetetrahydrofolate reductase (MTHFR) creates an enzyme with decreased affinity for its direct substrate, 5, 10 methylene-THF, which can cause a buildup of homocysteine. This means that some people make more homocysteine than others, and at this time you are able find out if this applies to you.
Those who make more homocysteine would especially benefit by increasing Folate in their diet, as well as starting dietary supplements that are clinically shown to decrease homocysteine.
Another example relates to individuals with the SNP for paraoxonase-1 (PON-1) who have an enhanced tendency for superior cardiac health because they more effectively block oxidation of LDL cholesterol. This means these people will have less oxidized LDL cholesterol than others. This SNP can also determine how effective vitamin C and vitamin E are as antioxidants in specific individuals.
How accurate is GeneWize Life Science’s DNA assessment technology?
Several techniques are used to determine DNA polymorphisms (SNPs). GeneWize LifeMap Healthy Aging Assessment™ uses the Single Base Chain Extension (SBCE) assay, which is the most precise method available and which recognizes the SNP directly on the DNA. The profile precision is nearly 100%. Additionally, the assay is performed mechanically and the DNA strand is assessed in both directions, which virtually eradicates human error in sample manipulation. To ensure accuracy, Coriel and sentinel samples are habitually used to test and confirm the results.
Will I need a prescription for the evaluation?
No. The GeneWize LifeMap Healthy Aging Assessment™ is categorized as non medical test and does not require a physician’s prescription. But, many healthcare practitioners are administering genetic appraisals as a way to help them provide personalized preventive healthcare to their patients.
What is GeneWize Life Science’s privacy policy?
GeneWize Life Science’s compliments the privacy of every individual and has taken many safety measures to create a process that allows those to maintain the highest level of privacy. All information provided by the individual taking the evaluation is kept on a secure server and all samples are recognized by barcode only. This information is never shared with a third party. After the assessment is finished and validated, all DNA sample material is destroyed.
Why is the LifeMap Healthy Aging Assessment™ an efficient way to help manage aging?
GeneLink’s Scientific & Medical advisory board has developed a 12-gene Healthy Aging DNA Assessment™ that measures SNPS (single nucleotide polymorphisms) or variations in key biochemical pathways that are vital to your body’s complete health. All of the SNPS in this panel have been validated by GeneLink’s Scientific & Medical Advisory board and by sovereign 3rd party scientific research.
Can I acquire a Health Aging DNA Assessment only?
Even though you can purchase a DNA assessment independently for $229.00, the LifeMap Nutrition System is intended to provide a resolution rather than simply provide a test result. As a result they make it economically appealing to order the entire system (which includes your 30 day supply of the LifeMap Essentials) for $199.00, considerably less than the price of an evaluation by itself. It’s your choice.
Does the buccal cheek swab DNA analysis offer the same information as with blood sample or other body parts? A cheek swab collection is simple but is it the best DNA to sample?
Most DNA testing is done today using samples collected via buccal swabbing, or cheek swabbing. Scientists have the same opinion that buccal swab samples are just as reliable as blood samples for DNA testing. DNA is the equivalent in every cell of the body. A cheek cell collected through buccal swabbing holds the same DNA as a blood cell collected through a blood draw. On the other hand, buccal swab samples have these primary benefits: Buccal swabbing is straightforward to do. Buccal swabbing is simple and noninvasive. It can even be safely performed on a newborn infant. Buccal swabs are more dependable than blood samples for patients who’ve recently had blood transfusions or bone marrow transplants. Such patients’ blood may display the presence of the donors’ DNA.
How can understanding your genes give you a longer, improved life?
Your health is a consequence of interactions between your genes and lifestyle factors such as diet, training, stress, smoking and alcohol. It is your genetic makeup that determines which nutrients are utilized and how they are used; the way toxins are removed, what occurs to any waste products and how efficient and effective these key processes are working within your body. But, by adjusting your lifestyle and utilizing a targeted nutritional supplement regimen, you can have a positive influence on how your genes work and compensate for region in which your genes are not functioning at a most favorable level.
Is there any insurance compensation for these DNA assessments?
No. The GeneWize LifeMap Healthy Aging Assessment™, while highly sophisticated, is a non-medical process.
Does the service offer any advantage that I wouldn’t get if I followed all the good advice from health care specialists, research organizations, magazine articles, specialized health care charities, etc.?
Even if you follow all of this guidance to the letter, it is still worth knowing your genetic nutritional profile. Particularly, the people who will find the service to be of considerable value are those who need an further bit of motivation to maintain healthy habits, or those who find it easier and more realistic to concentrate on areas particularly important for them while still being able to pamper (in moderation ) in some dietary or lifestyle preferences.
Are gene differences always harmful?
No. Many gene variations have no consequence on our body systems or our health and in certain cases these variations can even be helpful. However, sometimes a variation can make the gene send misinformation to the cell. Upon receiving the garbled message, the cell will produce a product – such as an enzyme – that doesn’t work exactly (or as efficiently) as it should; the alternative enzyme may, for example, work faster or more gradually than is best for the body. Combined with an unhealthy diet or lifestyle, such a gene variation may make a person more vulnerable to developing certain circumstances or in some cases certain illnesses.
If I have variations in my genes, can these be rectified?
Genes are found in every cell of the body. Consequently, for the correction to be effective, scientists must find a way to reach every single cell. This is a vast challenge for gene therapy, an experimental process that is attempted only in serious genetic diseases caused by a single flawed gene, such as cystic fibrosis. In contrast, the variations screened for by GeneWize are fairly ordinary in the general population, and their presence does not, by any means foresee that you will become ill. It would thus be both unfeasible and unsuitable to attempt to physically correct these commonly happening variations – even if the technology existed to make this possible.
GeneWize Life Sciences™ is not involved in researching gene treatment, and we do not offer treatment or cures of any kind. To a certain extent, we provide advice that takes into account the occurrence of genetic variations. Our service allows you to maintain good health by customizing a nutritional supplement routine tailored to your unique genetic profile.
Can the Healthy Aging Assessment tell me if I will cultivate a serious inherited illness, such as Huntington’s disease?
No, they don’t screen for any hereditary disorders that are not affected by diet and lifestyle, such as Huntington’s disease. These are comparatively rare disorders, known as single-gene diseases because they are caused by a flaw in only one gene.
Will the Healthy Aging Assessment decipher my complete genome?
No, decoding a complete genome is an enormous task. The Human Genome Project has mapped and deciphered the entire genomes of only a few individuals; this has taken many years of work and an international arrangement of research centers to accomplish. They are fortunate to be able to benefit from what has been discovered thus far in this complex and exhilarating project and GeneWize Life Sciences™ can deliver some of the benefits immediately to health conscious customers like you in a simple, accurate yet inexpensive service.
They examine only a restricted number of specific SNPs in the whole genome; these SNPs for the most part are heavy lifter SNPs recognized to code for metabolic enzymes that are vital to long term health and wellbeing.
Will the Gene SNP test be capable to tell me whether I am ill?
No, they can only establish what type of genes SNPs people have and how they relate to certain metabolic factors involved in wellbeing. In almost all cases, these genes will be the same whether a human being is well or ill. If you think you may be ill, you should check with your doctor.
Where do I find information on the research utilized?
All of the supporting scientific research information will be obtainable via PDF’s in each Affiliate’s Back Office. In addition, each LifeMap Healthy Aging Assessment™ contains multiple third party research and third party bibliography information associated to the SNPs tested. Each custom LifeMap™ Nutrition System product is shipped to customers and Affiliates with a personalized ingredient inventory included. Ingredient support information and third party research will also be accessible in each Affiliate’s Back Office.
If you have any other questions, contact Vincent Muir who is an independent affiliate of GeneWize Life Sciences who will happily guide you to any other information if available. Email Vincent at: vincent@geneinnercircle.com
I’d like to hear from you as your feedback is very important to me! Leave a comment down below with your thoughts on DNA assessments and don’t forget to tweet it if you liked it! (Or click on one of the icons below to share it with people you know!)
Related Posts:
|
|||
 |
|||
 |
|||
 |
|||
 |
Recent Comments